ICD-10-CM F43.23

ICD-10 Code F43.23: Adjustment disorder with mixed anxiety and depressed mood

F43.23 is the ICD-10-CM code for adjustment disorder with mixed anxiety and depressed mood. It is one of the most common adjustment disorder codes in outpatient therapy.

Official description
Adjustment disorder with mixed anxiety and depressed mood
Billable
Yes
Parent category
F43.2 · Adjustment disorders
DSM-5-TR name
Adjustment disorder, with mixed anxiety and depressed mood

Verified against the FY2027 ICD-10-CM code set (CDC/NCHS and CMS), effective October 1, 2026 - September 30, 2027, on . Chapter 5: Mental, Behavioral and Neurodevelopmental disorders (F01-F99).

Coding notes for F43.23

  • Both anxiety and depressed mood are prominent
  • If one clearly predominates, F43.21 or F43.22 is more specific
  • Document the stressor and when it began

What to document for medical necessity

Payers look for a record that supports the diagnosis and the level of care. For adjustment disorders that usually means:

  • The identifiable stressor and when it started
  • The predominant symptoms, which decide the sixth character
  • Why the reaction is out of proportion to the stressor or impairs functioning
  • A review date - adjustment disorders are expected to be time-limited, so revisit the code if symptoms persist
  • Treatment plan goals tied to the stressor and the symptoms

CPT codes often billed with F43.23

The ICD-10 code says why you are treating the client and the CPT code says what you did. These are the service codes most often paired with F43.23:

Free templates for this diagnosis

Related ICD-10 codes

Frequently asked questions

What is the ICD-10 code for adjustment disorder with anxiety and depression?

F43.23, Adjustment disorder with mixed anxiety and depressed mood.

Can F43.23 be used with a Z code?

Yes. A Z code can be added to describe the stressor, such as a relationship or work problem, alongside F43.23.

This page is a coding reference, not clinical, diagnostic, billing, or legal advice. The diagnosis is the treating clinician's call, and payer rules vary - always confirm against the current ICD-10-CM code set and official guidelines and your payer's policy. See the full mental health ICD-10 code list.